Latest axolotl research
Newest papers on Ambystoma mexicanum in the HerpAtlas research library, updated automatically.
- PROFET predicts continuous gene expression dynamics from scRNA-seq data to elucidate heterogeneity of cancer treatment responses.
Cheng YC, Gu H, McDonald TO et al. · Cell systems · 2026-08
- Histomorphological characterization of major tissues and organ systems in neotenic Ambystoma mexicanum.
Zapata-Cardona J, Lopez-Carvallo AM, Carbonell-Medina B · Acta histochemica · 2026-08 · open access
- Protocol for non-invasive genotyping of axolotls using skin swabbing.
Arbanas LI, Rodrigo Albors A · STAR protocols · 2026-08 · open access
Fin clipping is the standard method for sampling axolotl DNA for genotyping, but it requires anesthesia and removing a piece of tissue. Here, we present a non-invasive protocol for axolotl DNA sampling and genotyping using skin swabbing. We describe the steps for extracting DNA from skin cells…
- Exploring the ecological drivers of bacteriophage diversity and functional viral potential in the skin of the axolotl Ambystoma altamirani.
Cisneros-Martínez AM, Flores Varela MÁ, González-Serrano F et al. · FEMS microbiology ecology · 2026-08 · open access
- Systematic Necropsy and Tissue Sampling in the Neotenic Axolotl (Ambystoma mexicanum).
Cano-Botero A, Zapata-Cardona J, Carbonell-Medina B et al. · Current protocols · 2026-08
- Neoteny and Evolutionary Strategy: Reconsidering Developmental Arrest in the Axolotl and the Olm.
Mussies M · Acta biotheoretica · 2026-07 · open access
This article examines neoteny and regressive evolution in two emblematic amphibian species: Ambystoma mexicanum (axolotl) and Proteus anguinus (olm). Rather than framing larval persistence and trait loss as evolutionary shortcomings, the paper proposes an alternative interpretation in which…
- Histone and non-histone protein acetylation in a tail regeneration model (Ambystoma mexicanum).
Timoshevskaya N, Cecil RF, Schwartz J et al. · Biology open · 2026-07 · open access
Histone deacetylase inhibitors (HDACi) potently inhibit appendage regeneration, but how HDACi alter protein acetylation is relatively unexplored. Using genomic, transcriptomic, and proteomic approaches, we report HDACi-mediated changes in gene expression and protein acetylation at the outset of…
- Development of whole-limb skeletal patterning through the coordination of growth and self-organization models.
Ben Tahar S, Comellas E, Duerr T et al. · PLoS computational biology · 2026-07 · open access
The vertebrate limb provides an interesting system to study how tissue growth and molecular signaling interact to shape complex skeletal patterns. How these processes are coordinated across space and time is not fully understood. This study introduces a computational tool to examine how growth…
- Genome-Wide Analysis of an Endangered Axolotl Endemic to Mexico Reveals Genomic Variation Associated with Body Condition, Environment, and Infection by a Pathogenic Fungus.
Soto-Cortés E, Basanta MD, Ávila-Akerberg V et al. · Genome biology and evolution · 2026-07 · open access
- Temperature-Dependent Modulation of Cardiac Metabolism, Post-Injury Survival and Regenerative Rate in Axolotls.
Dittrich A, Andersson SA, Alstrup AKO et al. · Metabolites · 2026-06 · open access
Background/Objectives : Cardiac regenerative ability varies in vertebrates. Adult mammals cannot mount a regenerative response, while fetal mammals and some salamanders and teleosts fully regenerate the heart after a cryoinjury mimicking a myocardial infarction. This contrast is suggested to be…
- AXOLOTL: an accurate method for detecting aberrant gene expression in rare diseases using coexpression constraints.
Xu W, Shen Y, Liu X et al. · Bioinformatics (Oxford, England) · 2026-05 · open access
Motivation The assessment of aberrant transcription events in rare disease patients holds great promise for enhancing the prioritization of causative genes-a strategy already widely adopted in clinical settings to improve diagnostic accuracy. Nevertheless, the accurate identification of causal…
- The future of power forecasting: neuromorphic-axolotl hybrid intelligence revolutionizing grid operations through bio-inspired missing data mastery.
Alhag SK, Elbaz M, Moghanm FS et al. · Scientific reports · 2026-04 · open access
- The adrenal stress response involves distinct dynamics of both cortisol and corticosterone in the axolotl salamander.
Dittrich A, Andersson SA, Winkel EAB et al. · Lab animal · 2026-03 · open access
Main The axolotl salamander Ambystoma mexicanum (Shaw and Nodder, 1798) is a popular model organism in the fields of aging, development and, most prominently, tissue regeneration, owing to its ability to fully regenerate amputated limbs, as well as damaged or lost tissue in the heart, spinal cord,…
- Gonadal Development in Larvae of the Paedomorphic Ambystoma mexicanum (Amphibia: Urodela).
Sánchez-Ortiz JL, Mendoza-Cruz E, Villagrán-SantaCruz M · Journal of morphology · 2026-03 · open access
- Exploring Larval Axolotl Brain Development: Insights Into Developmental and Functional Constraints.
Houle L, Larouche O, Cloutier R · Evolution & development · 2026-03 · open access
Brain evolution in vertebrates has been conceptualized through two major hypotheses: the mosaic and concerted evolution models. The mosaic evolution model suggests that brain structures are primarily shaped by functional constraints, whereas the concerted evolution model emphasizes the role of…
- FGF2 rescues denervation-induced muscle atrophy in Ambystoma mexicanum.
Nakayama H, Ohashi A, Yamamoto S et al. · Skeletal muscle · 2026-02 · open access
- Axolotls retain fertility throughout lifespan.
Haluza Y, Gruhl B, Wagner A et al. · BMC biology · 2026-02 · open access
Background Salamanders such as axolotls exhibit exceptional regenerative abilities and longevity. While many ectothermic species reproduce into old age, axolotls have been proposed to experience post-maturation fertility decline. Results We hereby present a large-scale assessment of axolotl…
- Eimeria in the Xochimilco axolotl Ambystoma mexicanum.
Vázquez-Carlos A, Gual-Sill F, López-Díaz O et al. · Diseases of aquatic organisms · 2026-01
- Unique TCR loci architecture in newts: TRA and TRD separation in Pleurodeles waltl .
Migalska M, Babik W · Frontiers in immunology · 2025-11 · open access
T cell receptors (TCRs) are central components of the adaptive immune system, yet the genomic organization of TCR-encoding loci is highly complex and has been fully characterized in only a handful of vertebrate taxa. Many important lineages remain largely uncharted, with notable gaps in ectothermic…
- Optimized toolkit for the manipulation of immortalized axolotl fibroblasts
Tajer BJ, Kalu G, Jay S et al. · Methods · 2025-08
- Streptozotocin induced hyperglycemia in the axolotl.
Sørensen PL, Dittrich A, Lauridsen H · Developmental dynamics : an official publication of the American Association of Anatomists · 2025-07 · open access
Background Diabetes is a group of diseases characterized by loss of β cell mass and/or function, resulting in hyperglycemia. With no established curative treatment, this has initiated research in β cell regeneration. Current animal models have either limited regenerative capacity (mice) or small…
- The impact of size and ontogeny on suction feeding kinematics in the axolotl (Ambystoma mexicanum).
Toussaint-Lardé I, Louppe V, Sanchez-Garrido F et al. · Biology open · 2025-07 · open access
Size impacts all aspects of life in animals. Not only does it impact metabolism and physiology, it also affects movements, resulting in different selective pressures on animals of diverse sizes. However, beyond size, differences in developmental stage may also impact movements due to the maturation…
- Persisting at the Edge of Ecological Collapse: The Impact of Urbanization on Fish and Amphibian Communities From Lake Xochimilco
Alejandro Maeda Obregon, Elizabeth L. Clare, Luís Zambrano et al. · Environmental DNA · 2025-07 · open access
ABSTRACT Freshwater ecosystems are globally threatened by habitat loss, pollution, and invasive species, all of which are particularly acute in urban areas. To assess the impacts of urbanization on freshwater biodiversity—specifically the effects of alien species on native primary aquatic…
- Acute myeloid leukemia in a genetically related captive population of axolotls ( Ambystoma mexicanum ).
Lo M, Badial PR, DiGeronimo PM et al. · Veterinary pathology · 2025-05
- Influence of semicircular canal morphology on the VOR and swimming activity in larval amphibians: a comparative study in Xenopus and axolotl.
Schneider-Soupiadis P, Forsthofer M, Schneider-Soupiadis F et al. · Frontiers in neurology · 2025-05 · open access
Gaze stabilization and locomotion rely often on an accurate sensory detection of head movements by the vestibular system. A functional relationship between vestibular sensitivity, locomotor skills and semicircular canal morphology has been suspected in vertebrates as an adaptation to…
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